https://nova.newcastle.edu.au/vital/access/ /manager/Index en-au 5 https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:25125 in vitro drug release. The percent yield of microspheres was in the range of 75.2-87.3%. The particle size of microspheres was found to be in the range of 73.2-85.5 µm. Fourier transform-infrared spectral analysis and differential scanning calorimetry concluded the absence of any interaction between the drug and the carriers. The release time profile of metoprolol tartrate from microspheres in 0.1 N hydrochloric acid solution was to the extent of 33.4-60.2%. The complete release of metoprolol tartrate occurred from MPT-3 and MPT-4 in phosphate buffer solution (pH 7.4) within 8 and 7 h, respectively, whereas the incomplete release (72.3%) occurred from MPT-1. Nearly, the complete release (98.5%) of metoprolol occurred from MPT-2 in 10 h. Formulation MPT-2 would be a preferred formulation. The release of metoprolol involves diffusion rate limited (R² = 0.9865) as a mechanism from drug release. The prepared microspheres of metoprolol tartrate eliminate the need for multiple dosing and provide patient compliance.]]> Wed 11 Apr 2018 14:55:45 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:30390 Ulrichs), Journal Citation Reports (JCR), SCImago Journal & Country Rank (SJR), Google Scholar Metrics (GS), and Cabell’s Periodical Directory (Cabells). It describes the 13 indicators (variables) that are available through these databases—scholarly impact, subject category, age, total articles, distribution medium, open access, peer review, acceptance rate, pricing, language, country, status, and issue frequency—and highlights the similarities and differences in the ways these indicators are defined and reported. The study also addresses the ways in which this kind of information can be used to better understand particular journals as well as the scholarly publishing system.]]> Wed 11 Apr 2018 09:41:57 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:30388 Tue 05 Feb 2019 10:30:54 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:20833 Sat 24 Mar 2018 08:05:55 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:17748 2 was performed using two techniques, namely, the induction period and iso-conversional methods. The modelling and analysis arising from thermogravimetric studies of the material gave rise to the pre-exponential factor and, most importantly, the activation energy for the transition. Analysis using the induction period showed the activation energy to increase linearly with extent of conversion, ranging from 109–250 kJ mol⁻¹, while the iso-conversional method gave values in the range 66–76 kJ mol⁻¹, with higher values for both lower and higher extents of conversion. Comparison of these methods indicates that the iso-conversional method is the preferred technique for determining the kinetic parameters for this process. Overall, this allows for the determination of the optimum heat treatment temperature and time for the γ-MnO₂.]]> Sat 24 Mar 2018 07:57:20 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:25549 Sat 24 Mar 2018 07:26:05 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:3431 Sat 24 Mar 2018 07:20:25 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:39743 Mon 29 Jan 2024 18:49:33 AEDT ]]>